Higuain and Dybala start for Juventus at Wembley
The Argentina international missed Juve's last two matches with an ankle knock, but returns for the second leg of the last-16 tie at Wembley.
Higuain scored a brace in a 2-2 draw in Turin in the opening leg, the striker missing the chance to hit a hat-trick by thumping a penalty against the crossbar.
Partnering Higuain up front is his compatriot Paulo Dybala, the forward back after missing the first leg with a hamstring injury.
Juventus XI: Buffon; Barzagli, Benatia, Chiellini, Alex Sandro; Khedira, Pjanic, Matuidi; Dybala, Higuain, Douglas Costa
Bench: Szczęsny, Rugani, Lichtsteiner, Asamoah, Marchisio, Sturaro, Bentancur #TOTJuve #UCL #TOGETHER
— JuventusFC (@juventusfcen) March 7, 2018
With Serge Aurier suspended, Kieran Trippier starts at right-back for Tottenham and Ben Davies is preferred to Danny Rose on the left, while Mousa Dembele has shaken off a knock to line up in midfield.
As expected, centre-back Toby Alderweireld is not fit enough to be included in the Spurs squad, with Davinson Sanchez partnering Jan Vertonghen in defence.
#THFC : Lloris (C), Trippier, Sanchez, Vertonghen, Davies, Dier, Dembele, Eriksen, Dele, Son, Kane. #COYS pic.twitter.com/NNToY2RoiB
— Tottenham Hotspur (@SpursOfficial) March 7, 2018