Новости за 12.04.2024

Study details how nutrient-starved cells divert protein transport stations to cellular recycling centers to be broken down, highlighting a novel approach cells use to deal with stressful conditions.

Engineers have developed the smallest implantable brain stimulator demonstrated in a human patient that could revolutionize treatment for drug-resistant depression and other psychiatric or neurological disorders.

A third of the nearly 20 million women who participated in a national health survey reports migraines during menstruation, and of them, 11.8 million, or 52.5%, were premenopausal.

The typical job of the proteasome, the garbage disposal of the cell, is to grind down proteins into smaller bits and recycle some of those bits and parts. That's still the case, for the most part, but researchers, studying nerve cells grown in the lab and mice, say that the proteasome's role may go well beyond that.

A recent study uncovers a pathway used during normal wound healing that has the potential to reverse IPF.

Marine researchers have mapped the density of one of the most endangered large whale species worldwide, the North Atlantic right whale, using new data to help avoid right whales' harmful exposure to commercial fisheries and vessel strikes. The resulting maps, spanning 20 years of whale observations, are publicly available to inform risk assessments, estimations of whale harm/disturbance, marine spatial planning, and industry regulations to mitigate risk to right whales.

Chimpanzees and bonobos are often thought to reflect two different sides of human nature -- the conflict-ready chimpanzee versus the peaceful bonobo -- but a new study shows that, within their own communities, male bonobos are more frequently aggressive than male chimpanzees. For both species, more aggressive males had more mating opportunities.

A deep dive into macroalgae genetics has uncovered the genetic underpinnings that enabled macroalgae, or 'seaweed,' to evolve multicellularity. Three lineages of macroalgae developed multicellularity independently and during very different time periods by acquiring genes that enable cell adhesion, extracellular matrix formation, and cell differentiation, researchers report. Surprisingly, many of these multicellular-enabling genes had viral origins. The study, which increased the total number of sequenced macroalgal genomes from 14 to 124... Читать дальше...

A research team has unearthed new findings which may help explain the connection between cancer risk and poor diet, as well as common diseases like diabetes, which arise from poor diet. The insights gained from this study hold promise for advancing cancer prevention strategies aimed at promoting healthy aging.

New research has shown that the presence of wetlands and retention ponds alongside major highways led to an average reduction of almost 75% in the mass of tire wear particles being discharged to aquatic waters. The researchers say that while the number of retention ponds and wetlands in the UK is quite small, the study has international significance as to the most effective ways to mitigate against the potential impacts of tire pollution on a global scale.

Scientists have summarized microbial food production strategies.

A collaboration unveils a novel strategy for identifying key proteins in organelle communication. This approach advances our ability to pinpoint proteins essential for organelle interactions within specific spatial and temporal contexts.

In the sun-scorched Pilbara region of north-western Australia, scientists have unearthed a mysterious creature from the shadows -- a new ant species called Leptanilla voldemort.

In 2022, astronomers discovered the brightest gamma-ray burst (GRB) of all time. Now, astronomers confirm that a 'normal' supernova, the telltale sign of a stellar collapse, accompanied the GRB. The team also looked for signatures of heavy elements like gold and platinum in the supernova. They found no evidence of such elements, deepening the mystery of their origins.

The rise of RNA viruses like SARS-CoV-2 highlights the need for new ways to fight them. RNA-targeting tools like CRISPR/Cas13 are powerful but inefficient in the cytoplasm of cells, where many RNA viruses replicate. Scientists have devised a solution: Cas13d-NCS. This new molecular tool allows CRISPR RNA molecules that are located within the nucleus of a cell to move to the cytoplasm, making it highly effective at neutralizing RNA viruses. This advancement opens doors for precision medicine and proactive viral defense strategies.

A study suggests that people with diets high in seafood may face a greater risk of exposure to PFAS -- the family of human-made toxins known as 'forever chemicals' -- than previously thought. The researchers stress the need for more stringent public health guidelines that establish how much seafood people can safely consume to limit their exposure, particularly in coastal areas where seafood is frequently eaten.

A star's magnetic field must be considered in order to correctly determine the characteristics of exoplanets from observations by space telescopes such as Kepler, James Webb, or PLATO. Researchers show that the distribution of the star's brightness over its disk depends on the star's level of magnetic activity. This, in turn, affects the signature of an exoplanet in observational data. The new model must be used in order to properly interpret the data from the latest generation of space telescopes... Читать дальше...

Consuming sugar-sweetened drinks in the first few years of childhood can be linked to poor diet patterns that increase the risk of obesity in later life, according to a new study.

Drugs that target opioid receptors sometimes have severe side effects. Thousands of people around the world die every day from overdoses involving opioids such as fentanyl. Researchers have taken a closer look at the molecular mechanisms of these active substances.

A study has disentangled the mechanisms behind one of the ways melanoma cancer cells develop resistance to treatment. The study found that, in response to some drugs, melanomas can 'break' parts of their BRAF gene, which is mutated in 1 in 2 melanomas. This helps the tumor create alternative versions of the protein which lack regions targeted by one BRAF inhibitors, one of the main drugs used to treat this type of cancer, making treatment less effective. The findings pave the way for alternative strategies to treat BRAF-mutated melanoma... Читать дальше...

It is one of the world's most spectacular sights -- huge flocks or 'flamboyances' of flamingos around East Africa's lakes -- as seen in the film Out of Africa or David Attenborough's A Perfect Planet. But new research has revealed how the lesser flamingo is at danger of being flushed out of its historic feeding grounds, with serious consequences for the future of the species.

When the brain has trouble filtering incoming information and predicting what's likely to happen, psychosis can result, research shows.